The prescribing information recommends using extreme caution when combining bupropion with other medications that lower the seizure threshold, including: Antipsychotics Benadryl (diphenhydramine) Flexeril (cyclobenzaprine) Tricyclic antidepressants such as Elavil (amitriptyline) Theophylline Ultram (tramadol) Corticosteroids If the combination is prescribed together, the healthcare provider will start with low doses and increase gradually if needed
Kirkegaard T et al (2010) Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology
Frequently Asked Questions What is the purpose of the Wegovy to Mounjaro conversion chart
Certain populations, including older adults and people following a vegan diet, are at a higher risk of vitamin B12 deficiencies and may benefit from taking a vitamin B12 supplement
Non-starchy vegetables such as leafy greens, broccoli, cauliflower, peppers, and zucchini are usually well-tolerated and provide essential vitamins, minerals, and fiber
Overall, these findings provide mechanistic insight into the white matter abnormalities observed in conditions characterized by cerebral hypometabolism